Adipogenesis And Nutrition - 1188 Words

According to our previous studies using the same dietary treatments, the expression of adipogenesis-associated factors was decreased in the AT of chicks fed the HF or HP diet compared with chicks fed the HC diet [13, 14]. Therefore, data from the present study were analyzed within each diet to focus on the effect of IP NPY injection. Based on mammalian studies, NPY stimulates adipocyte proliferation and differentiation [6]. Our group also reported that NPY promotes adipogenesis during the early and later stages of chicken preadipocyte differentiation [9, 15]. NPY exerts its functions by binding to a variety of NPY receptors (NPYRs), with the most well-known ones associated with appetite and adipose physiology being NPYR1, NPYR2 and†¦show more content†¦This supports that NPY enhances adipogenesis and triacylglycerol synthesis. However, NPY injection also decreased the expression of AGPAT2, ATGL, NPY and FABP4 in the clavicular fat of chicks fed the HP diet 3h post-injection and C/EBPÃŽ ±, FABP4 and PPARï  § in the abdominal fat of chicks fed the HF diet 1h post-injection. Our in vitro studies also reported that NPY treatment decreased the expression of C/EBPÃŽ ± and SREBP1 at day 4 post-induction of differentiation and PPARï  § at d 4 and 6 post-induction of differentiation, however, the expression of these genes was recovered at d 8 post-induction of differentiation [9, 15]. One may argue that the amount of NPY treatment time of the in vitro studies was substantially longer than the current study, therefore, 3 hours were simply not enough to see the effect of NPY treatment. However, another study of ours that performed IP NPY injection in a different chicken model showed that the effect of IP NPY injection on the expression of adipogenesis-associated factors was diminished at 12 h post-injection (Liu et al., 2017). Because the differences between the in vivo and in vitro studies, it is unclear how to compare the effective time of treatment. For example, in the in vitro study, NPY has direct access to adipocytes, however, NPY was injected into the peritoneum in the present study and it is unclear how much would have reached to the adipocytes, and how other cell types in the AT would affect the effect of NPY.Show MoreRelatedEffect Of Artificial Sweeteners On Body Weight And Caloric Intake1262 Words   |  6 Pagesbeverage can lead to reduced overall caloric intake. Finally, researchers Pandurangan, Park, and Kim (2014) studied the impact of aspartame on adipogenesis, or the formation of fatty tissue. When adipocytes were treated with aspartame, there was significantly reduced lipid accumulation as well as down regulation of chemical receptors critical for adipogenesis. Therefore, this information suggests â€Å"that aspartame may be a potent substance to alter adipocyte differen tiation and control obesity† (PanduranganRead MoreTurmeric Mouthwash4563 Words   |  19 Pageson a yellow silk thread around your neck References: 1. . Usha Lad amp; Dr. Vasant Lad. Ayurvedic Cooking for Self Healing(2006) 2. Duke, James, Ph.D. The Green Pharmacy Herbal Handbook 3. . Curcumin Inhibits Adipogenesis. (2009) The Journal of Nutrition: Our findings suggest that dietary curcumin may have a potential benefit in preventing obesity. Curcumin, a constituent of turmeric, acts by preventing the formation of fatty tissue. The study was conducted on mice fed a high-fat